Vinyl halides
Accela Chembio Inc 2-bromoindene | 5g | 10485-09-3 | MFCD06797863 | 98% | Shelf Life: 1800 Days | Light Sensitive
2-bromoindene | 5g | 10485-09-3 | MFCD06797863 | 98% | Shelf Life: 1800 Days | Light Sensitive
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 5 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor (IC50 values of 1 nM against CK2α and CK2α'). It induces cell-cycle arrest and selectively causes apoptosis in cancer cells, attenuates PI3K/Akt signaling, and demonstrates antiproliferative activity correlating with CK2α catalytic subunit expression. It also prevents leukemic cells from engaging a functional UPR to buffer proteotoxic stress and decreases pro-survival ER chaperon BIP/Grp78 expression.
- Causes cell-cycle arrest
- Induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Exhibits antiproliferative activity
- Prevents leukemic cells from engaging a functional UPR
- Decreases pro-survival ER chaperon BIP/Grp78 expression
- Induces cytotoxicity
- Suppresses CK2-mediated PI3K/Akt/mTOR signaling pathways
- Demonstrates robust antitumor activity in murine xenograft models
Medchemexpress LLC Ponceau 4R (Acid Red 18; New Coccine) | 2611-82-7 | 85.0% | 5 G
Ponceau 4R (85%) is a synthetic strawberry red azo dye used as a food coloring. It is synthesized from aromatic hydrocarbons and is stable to light, heat, and acid, but fades in the presence of ascorbic acid. It is intended for research use only.
- Synthetic colorant that may be used as a food coloring.
- Strawberry red azo dye.
- Stable to light, heat, and acid (fades in the presence of ascorbic acid).
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.
- Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
- Antiproliferative activity correlates with CK2α catalytic subunit expression.
- Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
- Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
- Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.
Cayman Chemical DmyoInositol3phosphate sodiu
Synthetic, pure phosphoinositol for signal transduction research; can be formed by the dephosphorylation of polyphosphate inositols such as Ins(3,4)P2 by inositol polyphosphate 4-phosphatase
Sigma Aldrich Fine Chemicals Biosciences Bromomaleic anhydride 9750G
BROMOMALEIC Bromomaleic anhydride 9750G
Cayman Chemical DmyoInositol1phosphate sodiu
A synthetic, pure phosphoinositol for signal transduction research; can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase
eMolecules 513-31-5 | 2,3-Dibromopropene | ChemScene | MFCD00000211 | 199.873 | C3H4Br2 | 80.000 | BrCC(Br)=C | 100g | 582647133
2,3-Dibromopropene | ChemScene | 513-31-5 | MFCD00000211 | 199.873 | C3H4Br2 | 80.000 | BrCC(Br)=C | 100g | 582647133
Medchemexpress LLC Flucloxacillin sodium | 1847-24-1 | 98.0% | C19H16ClFN3NaO5S | 1 ML
Flucloxacillin sodium is an active antibiotic effective against gram-positive and gram-negative bacteria. It is for research use only and not sold to patients. In a study with male Wistar rats, Flucloxacillin sodium (200 mg/kg; i.p.; three times/day, for 21 days) was effective against common bacterial strains in periprosthetic infection, leading to reduced germs in the biofilm and bone tissue.
- Active against gram-positive and gram-negative bacteria.
- Effective in reducing germs in biofilm and bone tissue in a rat study.
- For research use only.